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Description
Gut hormones like ghrelin ( hunger) & GLP 1 PYY ( hunger) signal to the hypothalamus' arcuate nucleus. Orexigenic (AgRP NPY) & anorexigenic (POMC CART) neurons integrate these signals, regulating food intake via Y1 Y5 & Mc4 Natural GLP 1 Alternatives For Weight Loss Nutritionally Yours GLP Activate: Hunger & Metabolism Support (sku: GLP Act) Triquetra Reviews on Judge.me GLP 1 receptor agonists How Wegovy, Ozempic, and Mounjaro work GLP1 Pills Are Now Available How They Differ From Injections Discover Magazine Main effects and mechanisms of vitamin B12 (B12) cobinamide (Cbi)GLP1 Download Scientific Diagram
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.8 ★★★★★
Based on 2017 reviews
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Product Reviews
★★★★★ 5
Great for harsh winters
I was recommended this product by ChatGPT as an effective and safe product that my wife (who is currently nursing) can use. We have been very mindful of certain additives and chemicals in our products and this was able to meet our requirements.
Separately in the harsh winter in the northeast, this has been extremely effective in protecting the lips
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Reviewed in the United States on January 29, 2026
★★★★★ 1
Ruined by Reformulation
New formula update: They ruined this product by reformulating. Used to be so hydrating, long-lasting, and the only thing that gave me relief from eczema. Now it is somehow SO drying, oily, and all around terrible. Judging by reviews here and on their website many customers are unhappy with the change. Done with Avene.
Original five star review: This is a great all around lip balm, but if you struggle with perioral dermatitis/eczema then you NEED this. If I'm experiencing a flare, I slather on cicalfate+ at night but I can't exactly walk around with that during the day which is where this lip product comes in. It is calming, hydrating, and long-lasting. I have gone through more tubes than I can count. This was my first time ordering through amazon and I am happy to report I received authentic Avene.
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Reviewed in the United States on June 1, 2022
★★★★★ 5
It’s a God Send
I had a rash all around my lips and my lips got extremely dried out and started to peel. I used Avene Cicalfate Restorative Lip Cream and it really soothed my lips with the moisture they needed, and you don’t need to use a lot of this product. I plan on buying this again. Just wish the tube was bigger! I use other Avene products and I’m extremely happy with them.
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Reviewed in the United States on April 6, 2026
★★★★★ 5
Will never use another moisturizer
Size: 16.9 Fl Oz (Pack of 1), Size: 16.9 Fl Oz (Pack of 1)
I will never use another moisturizer again. I have highly sensitive, allergy-prone skin, and this is hands-down the best moisturizer I have ever found. It provides deep, long-lasting hydration that actually stays with you throughout the day.
I also suffer from Keratosis Pilaris (KP), and this lotion has worked wonders for clearing up and smoothing out those stubborn bumps. It comes in a giant bottle that lasts a long time.
The lotion itself is quite thick, so it feels slightly greasy for a brief moment right when you apply it, but it soaks in incredibly fast. Amazingly, despite how rich and thick the formula is, it has never clogged my pores or caused breakouts. If you have dry, sensitive, or bumpy skin, you need to try this!
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Reviewed in the United States on May 15, 2026
★★★★★ 5
Excellent, thick, and absorbent after a bit!
Size: 16.9 Fl Oz (Pack of 1)
Wanted the thickest, toughest, best moisturizer I could get for extremely dry, flaky, and all-around lousy skin.
This is it.
It's thick. Doesn't absorb immediately; you may have to work a little. Can leave a little odd (even slightly sticky) texture on your hands, but only for a very brief period. No visible signs except making your skin look better.
The results are excellent. Vastly prefer it over HylatopicPlus, which is a prescription lotion. My mother tried it and bought her own!
Also doesn't have lanolin like the original. FYI, apparently the USA version does *not* have Shea (which is a nut) but some international versions do. I'm in the USA and both mine were Shea-free. The listing here shows both ingredient lists in the pictures. If this is a factor for you, make sure to check.
All told, will be using this as my main moisturizer.
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Reviewed in the United States on November 17, 2025
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