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GLP 1 receptor agonists got their start in an unlikely place: the mouth of a lizard. A peptide that was discovered in Gila monster saliva, called exendin 4, was found to mimic the action GLP 1 Consultation in Glendale CO AFC Glendale Cherry Creek Weight Management What is the difference between semaglutide, tirzepatide, and retatrutide? Swipe to see how their mechanisms compare and who they may be used for. Firstwhat's an agonist? A drug that binds to GLP 1s like Ozempic are among the most important drug breakthroughs ever Podcast Episode 18 The Lion, the Leptin, and the GLP 1 GLP 1 Agonists: Revolutionizing the Treatment of Obesity, but Are They Enough? Eric Velazquez, MD Bariatric Surgeon Longstreet Clinic Center for Weight Management Atlanta, Georgia
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.7 ★★★★★
Based on 821 reviews
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Product Reviews
★★★★★ 5
Nice shoes!
Size: 11, Color: Black Full Grain
I bought them in black and I like them so much I will be buying the brown soon. They fit true to size and are comfortable and stylish. I like the clean simplicity. They're basically a dressy sneaker which is perfect for my job's 'dress code'. Yet they're stylish enough to be worn weekends or a night out. They seemed just a touch stiff out of the box but IMO that's completely normal and fine - after just a couple days of wearing them they are breaking in nicely. No complaints on that. They seem to be of very high quality and I'm very happy with them.
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Reviewed in the United States on February 8, 2026
★★★★★ 5
Good shoes!!!!!
Size: 10, Color: Tan Full Grain
They are comfortable, they fit, great style. I bought blue, brown and black shoes.
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Reviewed in the United States on August 18, 2025
★★★★★ 5
Great Product
Size: 13, Color: Black Full Grain
2nd Johnston & Murphy comfortable and stylish.
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Reviewed in the United States on December 26, 2025
★★★★★ 5
Great shoes for business casual, corporate travel
Size: 8.5, Color: White Full Grain
Fit true to size
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Reviewed in the United States on December 30, 2025
★★★★★ 5
Very Comfortable Shoes
Size: 11, Color: Black Full Grain
Were purchased as a gift and the wearer says they are the most comfortable shoes he has
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Reviewed in the United States on December 28, 2025
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